Role of Peptides in Diagnostics

The specificity of a diagnostic assay depends upon the purity biomolecules used as probe. To get specific and accurate information disease, use synthetic peptides in diagnostics have increased last few decades, because their high profile ability to modified chemically. discovered peptide probes are either imaging or non-imaging diagnostics. In diagnostics, techniques such Enzyme-Linked Immunosorbent Assay (ELISA), lateral flow devices (i.e., point-of-care testing), microarray LC-MS/MS for direct analysis biofluids. Among all, peptide-based ELISA is considered be most preferred technology platform. Similarly, can also techniques, single-photon emission computed tomography (SPECT) positron (PET). role radiolabeled peptides, somatostatin receptors, interleukin 2 receptor, prostate membrane antigen, αβ3 integrin gastrin-releasing peptide, chemokine receptor 4, urokinase-type plasminogen well established tools targeted molecular ortumor imaging. Low weight allow rapid clearance from blood result favorable target-to-non-target ratios. It displays good tissue penetration non-immunogenicity. only drawback using potential low metabolic stability. this review article, we discussed evaluated popular platforms discussed, categorized, ranked, per scientific contribution on PUBMED. Moreover, applicability deadly diseases, mainly COVID-19 cancer, detail.